ETF PRO AIOctober 4, 2026
XBI SPDR S&P Biotech ETF
Fund tearsheet · data as of the latest session · October 4, 2026
ONE YEAR OF DAILY CLOSES
0.35%expense ratio
$10.1Bfund assets
+26.7%return, YTD
+49.1%return, 1 year
−$658Mnet flow, 1 month
+$775Mnet flow, 1 year
28.1%realized volatility, 1y
-10.5%worst drawdown, 1y
Top ten holdings
| 1 | MRNA MODERNA | 1.41% |
| 2 | TWST TWIST BIOSCIENCE | 1.40% |
| 3 | IOVA IOVANCE BIOTHERAPEUTICS | 0.56% |
| 4 | GRAL GRAIL INC | 0.90% |
| 5 | NTRA NATERA | 1.16% |
| 6 | HALO HALOZYME THERAPEUTICS | 1.03% |
| 7 | RVMD REVOLUTION MEDICINES | 1.20% |
| 8 | KOD KODIAK SCIENCES | 0.54% |
| 9 | KYMR KYMERA THERAPEUTICS | 1.35% |
| 10 | PTGX PROTAGONIST THERAPEUTICS | 1.07% |
PREPARED WITH ETF PRO AI · PRIMARY MARKET DATA · INFORMATIONAL ONLY — NOT AN OFFER, RECOMMENDATION, OR INVESTMENT ADVICE · PAST PERFORMANCE DOES NOT GUARANTEE FUTURE RESULTS